Endocrine Abstracts

Introduction: Diabetic ketoacidosis (DKA) is a medical emergency, requiring careful fluid management and insulin administration. The guidelines published by the British Society for Paediatric Endocrinology and Diabetes (BSPED) in 2009 aim to standardise the approach to the management of paediatric DKA across NHS hospitals. Our aim was to report our experience in managing DKA in children in a district general hospital setting.Method: Retrospective case re...

Introduction: Diabetic ketoacidosis (DKA) remains a common presentation of type 1 diabetes (T1D) in children. During the COVID-19 pandemic, rates of presentation in DKA increased. Electrolyte abnormalities can occur during DKA treatment, but they are uncommon at presentation. We report a teenage girl with new-onset T1D presenting in severe DKA, complicated by profound hypokalaemia and hypernatremia. Case Report: A previously healthy 13-year-old girl was ...

Introduction: Neuropsychiatric manifestations are well recognised in patients with primary hyperparathyroidism (PHP). Abnormal calcium channel physiology has been implicated in several pain disorders. The psychopathology emerges after prolonged subclinical hypercalcemia, but there is poor correlation with symptom severity. We report the complex management of two adolescents with PHP, secondary to parathyroid adenoma (no predisposing germline mutation identified), with persiste...